USB may have issues connecting and syncing with your computer
Only one 'Watch TV' activity setting
If you're in need of just a single remote to control all your media player with the easiest setup, the Logitech Harmony 350 is for you. It can control almost all brand of media devices out there. You can only program one 'Watch TV' activity which is best suited for those with few media players to control. If you require lots of combinations of players to control, a higher end Harmony remote is better suited.